You can’t help but fall in love with Greenville, South Carolina. The city is one of southern charm, but unexpectedly so. The downtown is not stately antebellum homes, but rather brick buildings which are separated by pedestrian-only streets and a rushing river. Greenville is one of America’s fastest growing cities, and with all, there is to see and do, and buy and taste, it’s hard to keep up. There are dozens of cultural attractions like galleries and museums of history and art. The city has over 100 eateries and 120 shops and boutiques to explore. It’s also a city where you can interact with nature, either by biking on the Swamp Rabbit Trail or traversing the bridge in Falls Park that overlooks the waterfalls on the Reedy River. Greenville is a spot you’ll want to explore on foot, which is why you should choose an accommodation right downtown. If you want to see all that the city has to offer, here are 10 of the best HomeAway vacation rentals in Greenville.
We handpicked these listings carefully, considering (wherever possible) Superhost status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on October 11, 2025.
1. Condo on Earl Street district (from USD 79)
Enjoy the perks of a hotel with the independence and affordability of a vacation rental at this convenient accommodation. The apartment is located on historic Earl Street, one of the most beautiful streets in a lovely part of downtown. It has two bedrooms and can sleep up to five guests. Amenities include complimentary breakfast, concierge service, and laundry facilities. Parking is included for both cars and bikes, and pets are welcome with advance notice.
Greenville, South Carolina, United States
2.02 km (1.3 mi) from Falls Park on the Reedy
Top guest reviews
Host:
easy process and communicative owner is alway niceLocation:
this condo is in a great locationann's condo is on a nice quiet street within walking distance of downtownnice place great location and perfect ownerit’s a nice neighborhood for evening walks where everyone says hiin fact it was probably the best stocked place i've ever stayed inCleanliness:
condo was very clean& safeyour condo was clean and comfortable for a short or long term staya very clean and comfortable condo my husband and i enjoyed staying thereit was well stocked and cleanit was well stocked and super cleanRead more reviewsAmenities & Room:
the tv and internet were great and the furnishings finenice little apartment- perfect for a visit to greenvillethere were definitely moments we wanted an extra bathroomgreat space with lots of room in the master bedroomloved the historical neighborhood the apartment was in
2. Historic apartment for a family (from USD 214)
You’ll be utterly charmed by this cozy yet chic apartment steps from Main Street. With its exposed brick, hardwood floors, and huge windows that brighten the rooms, it is a gorgeous space for a reasonable rate. The apartment has one bedroom and can sleep up to four people with the options of cots or the queen-sized sleeper sofa. Guests can enjoy conveniences like laundry in the apartment and a parking garage. The apartment is centrally located, so feel free to leave your car and explore the sights of Main Street on foot. You can also rent bikes and take them on the nearby Swamp Rabbit Trail.
Greenville, South Carolina, United States
439 meters (0.3 ft) from Falls Park on the Reedy
Top guest reviews
Host:
host was exceptionally responsiveowner was extremely helpful with every detailthe hosts really care about their guests and it showstricia was a great host and we had an awesome timewe had a fantastic experience with the host and the condoLocation:
wonderful condo in an excellent location in downtown greenvillethe location is in a perfect place to explore downtown greenvillethe location is close to the peace center and main streeteasy walk to all of downtownspectacular property and location that was perfect for our long weekend in greenville and clemsonCleanliness:
very clean and well equippedwonderful property - great location very clean and well maintainedRead more reviewsAmenities & Room:
the space is warm comfortable and convenient easy access through an adjoining garage
3. Penthouse with fascinating terrace (from USD 212)
Live the high life in this penthouse right in downtown Greenville! The rental is a spacious one-bedroom apartment with room for up to four guests. The best part is the outdoor terrace, which has cozy seating and lovely views of Greenville. It is the ideal spot to wake up with a morning coffee or have a glass of wine while watching the sunset. The rental is just a block from downtown, making this a convenient yet luxurious starting point for sightseeing.
Greenville, South Carolina, United States
335 meters (0.3 ft) from Falls Park on the Reedy
Top guest reviews
Host:
property owner very responsivethe owner was very easy to communicate with and the home was exactly as it was postedLocation:
great location to enjoy the towneasy walk to all the hot spotswe loved the location and walking to restaurants and shops of greenvillecan’t beat the location and the place is so nice and well appointedwould definitely rent again great location clean & comfortableCleanliness:
very clean and well stockedexceptionally clean updated and beautifulthe unit was very nicely appointed and cleanRead more reviewsAmenities & Room:
a beautiful apartment with a great outdoor terrace and terrific furnishings and accomodationsdecorated with style yet super comfortable
4. Charming apartment on a quiet street
This quaint apartment oozes southern charm. You will feel right at home in the modestly yet tastefully decorated one-bedroom accommodation. Up to two guests can enjoy all the rental’s amenities, like a king-sized foam memory bed, laundry facilities, and secure wifi. The apartment is also pet-friendly so bring along your furry friends. If you will be staying in Greenville for an extended time, this would be a great option as the owner offers discounts on weekly and monthly stays. It is right next to the public library and art museum, so stay for a while and get to know the neighborhood.
1.49 km (1.0 mi) from Falls Park on the ReedyAccommodates: 2
Minimum Nights: 30
Refund Policy : 100% refund if you cancel at least 14 days before check-in.
Top guest reviews
Host:
I am giving a 5 star review with a couple of caveatsI can not say enough good things about Brooke and MichaelCeiling lights do not provide a warm atmosphereWe had everything we needed and more Definitely planning to visit againReasonably quiet especially being so close to downtownLocation:
The property is 4 or 5 blocks from Main St with its stores and restaurantsIt was very pleasant place to stay and easy walking distance to main street and downtownand it's many delicious restaurantsThis location was perfect for us as it was very close to downtown and easy to get toVery roomy and well thought out amenities Walked to the main street several times Nice quiet street Would definitely stay againCleanliness:
The apartment was clean well maintained and quite spacious (except for the bathroom)The house had everything we needed and Michael was congenial and very helpfulThe apartment is super clean and has all that you could need Large and clean eat-inWe were close to everything and really enjoyed our stayRead more reviewsAmenities & Room:
kitchen VERY comfortable bed comfortable living room with wifia nice comfy chair in the bedroom to sit and read along with that great bed would have made the bedroomAs I'm not much of a TVI found the bed comfortable but those who require a firm bed might not agreeThe home itself is fantastic Quiet and spacious
5. Spacious and colorful house for a large group
If you’re in need of a rental that can accommodate a large group of people, this home is for you. It has 6 bedrooms and can host up to 16 guests, ideal for families traveling together or a reunion of friends. The interior of the house is colorful and friendly, a perfect spot for kids or the young at heart. Each room has its own sink, TV, and Keurig maker, so no one will ever have to crowd the kitchen or bathrooms. The rental also comes with access to bike rentals to take on the Swamp Rabbit Trail. There are lots of other sights in walking distance, like Falls Park and the Pendleton Arts District.
570 meters (0.4 ft) from Falls Park on the ReedyAccommodates: 16
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 14 days before check-in.
Top guest reviews
Host:
She really came through for usWith Wendy's help guidance and flexibility we rented the entire Inn for our long weekendWe arrived early and were allowed an early check-inWendy's service and care was exemplary and she helped make our weekend more than memorableso the house is presented by a host who is clearly generous of heart and who has successfully created a very enjoyable atmosphereLocation:
Great property in a great locationThat seems to go a little too farWithin walking distance of grocery store restaurantsWe loved the location so close to Falls ParkIt was a short walk to downtown and a $5 Uber ride when we didn't want to walk Perfect weekendCleanliness:
The house and kitchen were clean inviting and ready for entertainment and dining Everything for a wonderful breakfastit was clean and very accommodatingThe "Indie Craft Parade" was definitely a highlight for our groupRead more reviewsAmenities & Room:
The 6 bedrooms accommodated everyone and the kitchendining living space is large enough for all of us to be in the space togetherThe kitchen was graciously stocked with everything one would need and even moreMy only complaint would be the web cam that is inside the house looking over the living room and kitchenwas right at our fingertips With a fully stocked fridge and plenty of coffee
6. Stunning home with unique character
This studio has a unique atmosphere and design you won’t find anywhere else. The exposed brick walls, wooden ceiling beams, and chandelier create a warm atmosphere. Touches like the weathered bathroom sink and freestanding French doors separating the bed from the living area give the place an antique feel. It is sized for up to four people and is spacious enough that it won’t feel cramped. There is a large balcony outside with a bistro table for dining al fresco. If you’re visiting in the summer months, visit the farmer’s market on Saturday mornings and bring back coffee, pastries, and other goodies!
345 meters (0.3 ft) from Falls Park on the ReedyAccommodates: 4
Minimum Nights: 1
Refund Policy : 100% refund if you cancel at least 30 days before check-in.
Top guest reviews
Host:
She always answered all questions promptly and was extremely niceOwner was great to work with If this spot is available do not hesitate to bookGreat location with Debbie as our great hostI already have family looking to book in the futureThe owner leaves soap paper towels foodstuffsLocation:
The location is amazing walking distance to so many restaurants yetThe location was awesome about a 2 minute walk to Reedy River and just steps into downtown shops and restaurantsThe location is less than a block from Main Street and excellent walkabilityEverything is in walking distancebut it is still very quietCleanliness:
Location can't be beat close to everythingThe Nest is not your "cookie cutter" condo rentalstill private and super quiet Wonderfully decorated Would definitely recommendRead more reviewsAmenities & Room:
that you are free to useIt really makes you feel like homeVery much to our likingSuch a cool place Comfy bed and great amenitiesOnce you park you do not have to get in your car again until you leave
7. Historic charmer with modern amenities
You’ll feel like you’ve been transported back in time in this lovely apartment. It is located in a historic building and elements of the antique structure are still visible, like the tall ceilings that let in lots of light. The decor echoes the past as well, with plush parlor chairs, rich wooden furniture, and historic paintings throughout the home. There is one bedroom, and a total of six sleeping spots for guests with a pull-out sofa in the living room, and two sleeping cots available. Though the apartment is close to the busy downtown streets, it is on a quiet block where you can relax and feel at home.
751 meters (0.5 ft) from Falls Park on the ReedyAccommodates: 4
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 30 days before check-in.
Top guest reviews
Host:
and she was very friendly and helpfulThe owner is very responsive as wellThe host reached out to us before our stay and we knew we could contact her if we needed anythingWe had a wonderful visit and enjoyed the Fall for Greenville festival which we walked to and the zooclose to all that Greenville has to offer Communication from the owner is excellentLocation:
but not a big dealIt is just a few blocks from Main Street and very cute and comfortable Also close to Publix grocery store and many restaurantsvery charming historic building restored nicely Downtown Greenville is a quick walk away andLove the location walking distance to everything downtownBeautiful home in a historic building within walking distance of downtown and the arenaCleanliness:
very clean and nicely decoratedThe apartment was very cleanSo clean - sweetly decorated - homey AND best locationIt was absolutely adorable and the court yard was also beautiful and very quietRead more reviewsAmenities & Room:
(shared room toddler in packThe bed was comfy even the pull-outn play)-kitchen could use a few more items(For us due to toddler & long stay)-unloading/loading (lots of stuff for toddler)-bed/pillows not super comfy & bed squeaked a lot when turning over/getting in/out of bedVery comfortable and well appointed place
8. Cozy suite in a stylish, historic home
This suite is located in a charming home that dates back to the 1920s. The interior has been fully renovated, and the owners used materials from the original building to give it an authentic historic vibe. The downstairs suite can accommodate up to six guests in two bedrooms. If you’re looking for a rental that can host more people, the suite upstairs can also be rented out if it’s available. This rental is within walking distance to Fluor Field, where the Greenville Drive baseball team plays, as well as Falls Park, the heart of downtown Greenville.
916 meters (0.6 ft) from Falls Park on the ReedyAccommodates: 6
Minimum Nights: 1
Refund Policy : 100% refund if you cancel at least 30 days before check-in.
Top guest reviews
Host:
stay and the owner was super easy to work withone of the owners is very responsive straight forward and pleasant to work withand we fell in love with the condoThe owners were very responsive and the home was beautifulWe spent two hours the first night trying to make it workLocation:
The location is just off of Main Street and very convenientStayed here for one night while in town to go to a play at The Peace Center Great location within walking distance orWe pick a different city to explore every NovemberThe house is within walking distance to plenty in downtown Greenville Highly recommendedThe location of the property is perfect for riding bikes or heading out for a great mealCleanliness:
The bedrooms are comfortable clean and also beautifully decoratedand we really appreciate the coffeeProperty is updated and beautifully decoratedThe place is clean spacious beautifully decorated comfortable and in a fantastic location very close to downtownshort Uber ride to everything Very well decorated with everything you needRead more reviewsAmenities & Room:
while in Greenville Very comfy master bed super cozy room for our girls with two single bedsbut they provide coffee and have plenty of counter space and a large fridge for your foodThe kitchen is not only beautifulThe condo was very spaciousAlso the TV was a bit of a disappointment My father likes to watch local news in the evenings and this was only internet TV which was new to us
9. Trendy condo in a great location
You can’t beat the location of this condo rental. It is right by Main Street and is within walking distance to many Greenville sights. You’ll be right across from The Peace Center for a concert and other cultural events. There is also a free trolley that will take you to all the other attractions, like the Children’s Museum or historical museum. The apartment has two bedrooms for up to four guests. It is spread across two floors and has lots of living space so you won’t feel crowded.
488 meters (0.4 ft) from Falls Park on the ReedyAccommodates: 4
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 14 days before check-in.
Top guest reviews
Host:
She was quick to answer any questionsThe host was very accommodating and helpfulgracious and went out of her way to make us feel welcomethe brick wall and exposed beamsWe arrived a little early and all was ready for us Music playing lights on snacks coffeeLocation:
It is a 2 minute walk to restaurants and shopsJust steps away from Main Street 14 minute walk to Bon Secours Wellness Area and 4 minuteThe location could not be better Half a block offThe location is fabulous if you want to walk to all the shops parks and restaurantswalk to the beautiful Falls ParkCleanliness:
The bedrooms and baths were very nicely appointedold and new We had everything we needed and the location couldn't be beatRead more reviewsAmenities & Room:
The condo is very spacious and comfortableComfy beds nice towels and toiletriesWe were treated to a crawling bug in the master bed room on first night3rd floor bedroom is private with hardwood floors(couple Uber rides too)
10. Cozy apartment for a steal
There is nothing wrong with seeking out the most affordable accommodation you can find while traveling. If a cheap nightly rate is your main criteria, check out this cozy one-bedroom apartment. Not only is it affordable, leaving room in your budget for all the attractions in Greenville, it’s also just as charming as any other rental on this list! Up to two people can stay in the apartment, which is bright with minimalistic decor. It has a private entrance, a spacious kitchen, and a living room with Netflix and local TV channels. The rental also has its own courtyard with a table and chairs, where you can sit and take in the friendly surrounding.
1.49 km (1.0 mi) from Falls Park on the ReedyAccommodates: 2
Minimum Nights: 30
Refund Policy : 100% refund if you cancel at least 30 days before check-in.
Discover why downtown Greenville is one of the best in the country
Greenville is often said to have one of the best downtown neighborhoods in America. It is friendly and welcoming, with pedestrian walkways designed to let you explore on foot. There is a free trolley around the city that will take you to all the cultural attractions there are to see. Falls Park is the heart of the city and often hosts festivals, concerts, and outdoor movies and plays that bring the community together. It’s no wonder that Greenville is getting so much attention, so book your vacation rental and start planning your own visit today.
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